Respuesta :
The participants are required to mention : " The most common cause of anaphylaxis is penicillin ".
What are the effects of penicillin on anaphylaxyis ?
Although aspirin, morphine (an opioid) and radiocontrast agents such as iodine can cause anaphylaxis, penicillin is the most comon cause of anaphylaxis, accounting for about 75% of fatal anaphylactic reactions in the United States each year.
A past exposure to penicillin causes preformed IgE responses, which lead to acute reactions. Mast cells release histamine and other mediators as a result, which causes the classic signs and symptoms of a real anaphylactic reaction.
Anaphylaxis can occasionally occur as a result of a penicillin allergy. It is a potentially fatal illness that can include dizziness or lightheadedness, breathing issues, throat or tongue swelling, seizures, extremely low blood pressure, vomiting, diarrhea, and cramps in the abdomen.
Penicillin causes anaphylaxis in between 0.02% and 0.04% of cases, and type 1 hypersensitivity reactions are the primary mediator.
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