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In actuality, the G-T mutation is the one that occurs most frequently in human DNA. It happens once every 10,000 to 100,000 base pairs, which doesn't sound like much until you remember that the human genome has about three billion base pairs.

Viruses, which can have either RNA or DNA genomes, have the greatest per base pair per generation mutation rates. The mutation rates of DNA viruses range from 106 to 108 mutations per base each generation, while those of RNA viruses range from 103 to 105 mutations per base per generation.

Cystic fibrosis, hemophilia, and sickle cell disease are examples of hereditary mutations. Throughout a person's life, other mutations may occur on their own. Spontaneous, sporadic, or new mutations are the terms used to describe them. Only a few cells are affected.

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